HBOT Protocol for aging

Hyperbatic Therapy with alternating hyperoxic oxygen administration has been proven to provides important benefits:

• Telemere increase
• Immunosenescence decrease
• Blood Cells senescen

Famous researcher Shai Efrati, made up Aviv Clinic where i went visiting in Dubai that provides the HBOT threatment with intermittent hyperoxic oxigen protocol, with a lot of measurements to evaluate the effective of telemere increase and extra-vascularization in the brain and other tissues via MRI.

You have to stay there for 3 months and bring around $130k + local cost of living, that’s very cool but not doable for me.

The purpose of this section is to keep tracks of setting up the Shai Efrati / Aviv Clinic HBOT protocol with your nearby HBOT-enabled center.

A couple of research paper to let the reader get deeper in the process:

• Hyperbaric oxygen therapy increases telomere length and decreases immunosenescence in isolated blood cells: a prospective trial
  • “In conclusion, the study indicates that HBOT may induce significant senolytic effects including significantly increasing telomere length and clearance of senescent cells in the aging populations.”

• Hyperbaric oxygen therapy: future prospects in regenerative therapy and anti-aging
  • “The intermittent HBOT treatment cycles create hyperoxic-hypoxic paradox, i.e., the body experiences a state of hypoxia without its hazardous effects and induces protective mechanisms in response to hypoxia. The fluctuations in tissue oxygen levels initiate a regenerative mechanism and direct the oxygen supply to the tissues where it is most needed. The extra oxygen supply is utilized in the process of healing, tissue repair, rebuilding and regeneration.”

Aviv Clinics HBOT for Anti-Aging

Aviv Clinics do implement Shai Efrati research on HBOT, i’ve been there in 2022 and their 3-months threatment for $130k was including 3 or 4 HBOT session with intermitent oxygen, plus a numbers of measurements (MRI, Blood, DNA).

I argue that HackingBiology should document the protocol being realized by Shai Efrati in research and for Aviv Clinics, to be doable at our own local HBOT Center.

The plan should be to describe the technical specification of the protocol and provide it to own local HBOT Center for implementation.

Intermittente Hypoxia-Hyperoxia Training as alternative to HBOT?

A very interesting alternative, to be analyzed in depth and in comparison to Intermittente HBOT, is the Intermittent Hypoxia-Hyperoxia Training (IHHT) whereby the oxygen modulation is provided at normal pressure.

Thanks to Manlio Lo Giudice from Zero Club community for the lead as alternative from HBOT (that have less accessibility, costs and greater contraints such as not being able to uses any electronics).

To starts learning i’d go Effectiveness of Intermittent Hypoxia–Hyperoxia Therapy in Different Pathologies with Possible Metabolic Implications

In Italy i am looking forward different HBOT Centers for my protocol practice

Centro Medicina Iperbarica Policlinico Umbero I (Rome)

ICOT Medicina Iperbarica (Latina)